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Researchers & Collaborators

Dr Brett Knowles

Dr Brett Knowles is a leading upper gastrointestinal surgeon at The Royal Melbourne Hospital, St Vincent’s Hospital Melbourne, St Vincent’s Private Melbourne, Epworth Health and the Peter MacCallum Cancer Centre and in private practice Melbourne Surgical Group.

A dedicated specialist and researcher in pancreatic cancer, Brett Knowles is the lead investigator for the DIRECT-InspIRE Nanoknife clinical trial, a Principal Investigator for the Pancreatic organoid project and a member of the PURPLE registry steering committee.

Associate Professor Charles Pilgrim 

A/Prof Charles Pilgrim is a leading upper gastrointestinal surgeon specialising in pancreatic cancer at the Hepato Pancreato Biliary Unit at The Alfred in Prahran, the Trauma Surgery Service at The Alfred and at the General and Emergency Surgery Unit at Frankston Hospital.

A dynamic researcher, A/Prof Pilgrim is the Principal Investigator (PI)  for both the IRE Nanoknife study and the PURPLE Translational Registry at Alfred Health, the MASTERPLAN trial at The Alfred and Cabrini, and the PanTher Trial at the Alfred. 

Recently awarded an Australian Government Medical Research Future Fund (MRFF) grant for the SCANPatient study, A/Prof Pilgrim is the PI for a nationwide study that will test a diagnostic radiology synoptic report designed to support the accurate assessment of a patient's suitability for pancreatic cancer surgery. 

A/Prof Pilgrim also consults at Upper GI Robotic Surgery at Cabrini Medical Centre and at the Peninsula Private Consulting Suites in Frankston.

Dr Hyun Ko

Dr Ko is a multilingual German and Australian board-certified radiologist and clinician researcher with 20+ years international radiology experience. 

Dr Ko is subspecialist fellowship-trained in breast imaging (Melbourne, AUS), imaging research (Toronto, CAN) and paediatric radiology (Heidelberg, GER).

Since her experimental laboratory-based medical doctorate (Mairbäurl, Effects of Hypoxia on NaK-ATPase in A549 epithelial lung cells), Dr Ko’s focus has been on harnessing clinical and research data to advance translational medicine. Her most recent research includes higher computational analysis, artificial intelligence, and radiomics to develop predictive imaging biomarkers. In recognition of her contribution, Dr Ko was chosen as one of six finalists at the 19th Annual Research Australia Award 2022.

She has won multiple national and international grants (e. g. Bonn-Melbourne Research Excellence Grant, Neuhauser Fellowship Award by the European Soc. of Paediatric Radiology and the Children’s Hospital Boston, USA).

Dr Ko is an active member of RANZCR Advisory Committee on Artificial Intelligence and of the German Roentgen Society (DRG) Working Party Methodology and Research.

A strong supporter of evidence-based medicine, Dr Ko believes in the strengths of multidisciplinarity and inclusiveness as key ingredients of research innovation and impact.

Professor Peter Gibbs

Prof. Peter Gibbs is a leading consultant medical oncologist and dedicated clinician researcher with a long-standing interest in translational research, cancer clinical trials and clinical data registries.

Peter is the Joint Division Head of Personalised Oncology and Head of the Gibbs Laboratory at WEHI.

Peter is a frequently-invited speaker at national and international expert meetings and holds an appointment as Professor at the University of Melbourne.

Associate Professor Tracy Putoczki

A/Prof Tracy Putoczki is a laboratory head in the Personalised Oncology Division at the Walter and Eliza Hall Institute of Medical Research. She is a Sylvia & Charles Viertel Charitable Foundation Senior Medical Research Fellow and recipient of the inaugural Australian Society of Medical Research Peter Doherty Leading Light Award. 

Tracy completed her undergraduate research training at the University of Toronto, Canada, where she completed an honours degree with a focus on angiogenesis. Following this, Tracy undertook a PhD in molecular biology and biochemistry at the University of Canterbury,  completing her postdoctoral training in Melbourne at the Ludwig Institute.

Tracy currently heads a team of researchers studying cell biology, molecular biology and structural biology techniques to understand how cytokines enable cancers to grow, metastasize and develop resistance to current treatments. The goal of the research is to understand the conversations that occur within the tissue microenvironment and learn how these impact the behaviour of cancer cells, and use this knowledge to develop new therapeutic opportunities for patients.

Laura Dagley

Laura is the Proteomics Facility manager at WEHI.

Laura's expertise focuses on proteomic experimental design and workflows, in both the clinical & disease specific settings. Laura provides proteomics advice for PURPLE Translational studies.

Laura completed her PhD in discovering novel disease markers of multiple sclerosis (MS), working across both The University of Melbourne/Bio21 Institute and the University of Toronto, Canada. 

Her postdoctoral research at WEHI focuses on the application of cutting edge technologies to address key research questions in the fields of disease biomarkers, inflammatory disorders and cancer. 

She is the recipient of several nationally-competitive awards including the Ken Mitchelhill Award from the Australasian Proteomics Society, and peer-reviewed competitive research grants from the NH&MRC and the AMP Foundation.



More information about us

PURPLE Registry

The PURPLE Registry was established in 2016 by a team of clinicians and scientists led by Dr Belinda Lee at WEHI.

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PURPLE Translational Initiatives

The PURPLE Registry supports a number of important pancreatic cancer initiatives including clinical trials, laboratory-based research and screening studies.

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Goals & Impact

To improve outcomes in pancreatic cancer, it is crucial that greater participation in and access to new drug treatment and clinical trials is encouraged.

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Meet the team

Meet the team behind PURPLE.

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Steering Committee

Meet our Steering Committee Members.

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Funders & Partnerships

The PURPLE Translational Platform is made possible through our generous funders and partnerships.

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